BDBM50113293 4-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazolidin-3-yl]-benzoic acid anion

SMILES: [O-]C(=O)c1ccc(cc1)N1C(=S)S\C(=C\C=C\c2ccccc2)C1=O

InChI Key: InChIKey=AEAPRFCJDOSCGL-LHQXNBGVSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50113293 (4-[4-Oxo-5-(3-phenyl-allylidene)-2-thioxo-thiazoli...) Show SMILES [O-]C(=O)c1ccc(cc1)N1C(=S)S\C(=C\C=C\c2ccccc2)C1=O Show InChI InChI=1S/C19H13NO3S2/c21-17-16(8-4-7-13-5-2-1-3-6-13)25-19(24)20(17)15-11-9-14(10-12-15)18(22)23/h1-12H,(H,22,23)/p-1/b7-4+,16-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptide				J Med Chem 45: 2213-21 (2002) BindingDB Entry DOI: 10.7270/Q2SB46F1
					More data for this Ligand-Target Pair