BDBM50113295 1-[5-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-yl]-3-phenyl-urea::CHEMBL72757

SMILES: Clc1ccc(cc1)-c1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1

InChI Key: InChIKey=DHWGXBSXKGMHQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50113295 (1-[5-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-yl]-3...) Show SMILES Clc1ccc(cc1)-c1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C22H17ClN4O/c23-17-13-11-16(12-14-17)20-15-21(27(26-20)19-9-5-2-6-10-19)25-22(28)24-18-7-3-1-4-8-18/h1-15H,(H2,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptide				J Med Chem 45: 2213-21 (2002) BindingDB Entry DOI: 10.7270/Q2SB46F1
					More data for this Ligand-Target Pair