BDBM50113331 (4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL74756

SMILES: Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1

InChI Key: InChIKey=JREBTSVEMYTHEU-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50113331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair