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BDBM50113351 CHEMBL3603910

SMILES: Fc1cccc(c1)-c1cc(ncn1)-n1cccn1

InChI Key: InChIKey=HKZPYJDJLRYASP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113351   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50113351
PNG
(CHEMBL3603910)
Show SMILES Fc1cccc(c1)-c1cc(ncn1)-n1cccn1
Show InChI InChI=1S/C13H9FN4/c14-11-4-1-3-10(7-11)12-8-13(16-9-15-12)18-6-2-5-17-18/h1-9H
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
 7.94E+3n/an/an/an/an/an/an/an/a



Heptares Therapeutics Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]-M-MPEP from human mGlu5 receptor expressed in HEK293 cells after 90 mins by scintillation spectroscopy analysis

J Med Chem 58: 6653-64 (2015)


BindingDB Entry DOI: 10.7270/Q2H70HMZ
More data for this
Ligand-Target Pair