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SMILES: Cn1cc(ccc1=O)-c1n[nH]c2CCN(Cc12)c1ccn(Cc2ccccc2)c(=O)c1

InChI Key: InChIKey=ULZMCYOFQYWMSL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113672   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (Human))		BDBM50113672
PNG
(CHEMBL3604846)
Show SMILES Cn1cc(ccc1=O)-c1n[nH]c2CCN(Cc12)c1ccn(Cc2ccccc2)c(=O)c1
Show InChI InChI=1S/C24H23N5O2/c1-27-15-18(7-8-22(27)30)24-20-16-28(12-10-21(20)25-26-24)19-9-11-29(23(31)13-19)14-17-5-3-2-4-6-17/h2-9,11,13,15H,10,12,14,16H2,1H3,(H,25,26)
PDB
MMDB

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PC cid
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Similars
PubMed
n/an/a 7n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of ERK2 (unknown origin)

Bioorg Med Chem Lett 25: 3626-9 (2015)


BindingDB Entry DOI: 10.7270/Q2QR4ZXX
More data for this
Ligand-Target Pair