BDBM50113721 1-[6-(3-Chloro-phenylamino)-9-isopropyl-9H-purin-2-ylamino]-indan-2-ol::CHEMBL79764
SMILES: CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NC3[C@@H](O)Cc4ccccc34)nc12
InChI Key: InChIKey=IGBPZQWXZJHJON-OYKVQYDMSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50113721 (1-[6-(3-Chloro-phenylamino)-9-isopropyl-9H-purin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Deutschland GmbH Curated by ChEMBL | Assay Description Binding affinity to cyclin-dependent kinase 1 (CDK1) | J Med Chem 45: 2366-78 (2002) BindingDB Entry DOI: 10.7270/Q25B01SB | |||||||||||
More data for this Ligand-Target Pair |