BDBM50113761 CHEMBL3604844

SMILES: Fc1ccc(cc1)-c1n[nH]c2CCN(Cc12)c1ccn(Cc2ccccc2)c(=O)c1

InChI Key: InChIKey=AVLKLAKUQZHOLX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50113761 (CHEMBL3604844) Show SMILES Fc1ccc(cc1)-c1n[nH]c2CCN(Cc12)c1ccn(Cc2ccccc2)c(=O)c1 Show InChI InChI=1S/C24H21FN4O/c25-19-8-6-18(7-9-19)24-21-16-28(13-11-22(21)26-27-24)20-10-12-29(23(30)14-20)15-17-4-2-1-3-5-17/h1-10,12,14H,11,13,15-16H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin)				Bioorg Med Chem Lett 25: 3626-9 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZXX
					More data for this Ligand-Target Pair