BDBM50113777 (4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hexahydrophenanthren-2(1H)-one::4a-Benzyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one::CHEMBL310180
SMILES: Oc1ccc2c(CC[C@@H]3CC(=O)CC[C@@]23Cc2ccccc2)c1
InChI Key: InChIKey=RMPXVMMQXKFIHM-UTKZUKDTSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50113777 ((4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hex...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptor | J Med Chem 45: 2417-24 (2002) BindingDB Entry DOI: 10.7270/Q2HT2Q1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50113777 ((4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hex...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Displacement of [3H]DEX from human glucocorticoid receptor | J Med Chem 53: 3065-74 (2010) Article DOI: 10.1021/jm901452y BindingDB Entry DOI: 10.7270/Q2VQ33NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen Receptor (Homo sapiens (Human)) | BDBM50113777 ((4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hex...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]DHT from human Androgen receptor | J Med Chem 45: 2417-24 (2002) BindingDB Entry DOI: 10.7270/Q2HT2Q1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50113777 ((4aS,10aR)-4a-benzyl-7-hydroxy-3,4,4a,9,10,10a-hex...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of radioligand from human Progesterone receptor | J Med Chem 45: 2417-24 (2002) BindingDB Entry DOI: 10.7270/Q2HT2Q1F | |||||||||||
More data for this Ligand-Target Pair |