BDBM50113794 CHEMBL82658::RS-4-{2-[2-(1-Carbamimidoyl-piperidin-4-yloxy)-ethyl]-piperidin-1-yl}-3-cyclooctylamino-4-oxo-butyric acid
SMILES: NC(=N)N1CCC(CC1)OCCC1CCCCN1C(=O)[C@H](CC(O)=O)NC1CCCCCCC1
InChI Key: InChIKey=VCWGHXLLKIVRCN-IAXKEJLGSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50113794 (CHEMBL82658 | RS-4-{2-[2-(1-Carbamimidoyl-piperidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin. | J Med Chem 45: 2432-53 (2002) BindingDB Entry DOI: 10.7270/Q2S181VR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50113794 (CHEMBL82658 | RS-4-{2-[2-(1-Carbamimidoyl-piperidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of human trypsin. | J Med Chem 45: 2432-53 (2002) BindingDB Entry DOI: 10.7270/Q2S181VR | |||||||||||
More data for this Ligand-Target Pair |