BDBM50114239 CHEMBL40166::N-(4-{4-[3-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-ureido]-phenoxy}-phenyl)-3-methyl-butyramide

SMILES: CC(C)CC(=O)Nc1ccc(Oc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1

InChI Key: InChIKey=DNSDEQOQPFJNQY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50114239 (CHEMBL40166 | N-(4-{4-[3-(5-tert-Butyl-2-methyl-2H...) Show SMILES CC(C)CC(=O)Nc1ccc(Oc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)cc2)cc1 Show InChI InChI=1S/C26H33N5O3/c1-17(2)15-24(32)27-18-7-11-20(12-8-18)34-21-13-9-19(10-14-21)28-25(33)29-23-16-22(26(3,4)5)30-31(23)6/h7-14,16-17H,15H2,1-6H3,(H,27,32)(H2,28,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 12: 1559-62 (2002) BindingDB Entry DOI: 10.7270/Q2CV4H28
					More data for this Ligand-Target Pair