null

SMILES: COc1cc(cc(OC)c1OC)C(=O)N\N=C\c1ccc(o1)-c1ccc(cc1)C(O)=O

InChI Key: InChIKey=VQSHFRADLUDATH-FSJBWODESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM50114405 (CHEMBL3609813) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N\N=C\c1ccc(o1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H20N2O7/c1-28-18-10-15(11-19(29-2)20(18)30-3)21(25)24-23-12-16-8-9-17(31-16)13-4-6-14(7-5-13)22(26)27/h4-12H,1-3H3,(H,24,25)(H,26,27)/b23-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrs				Eur J Med Chem 101: 63-70 (2015) BindingDB Entry DOI: 10.7270/Q2NS0WQM
					More data for this Ligand-Target Pair
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM50114405 (CHEMBL3609813) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N\N=C\c1ccc(o1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H20N2O7/c1-28-18-10-15(11-19(29-2)20(18)30-3)21(25)24-23-12-16-8-9-17(31-16)13-4-6-14(7-5-13)22(26)27/h4-12H,1-3H3,(H,24,25)(H,26,27)/b23-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric method				Eur J Med Chem 101: 63-70 (2015) BindingDB Entry DOI: 10.7270/Q2NS0WQM
					More data for this Ligand-Target Pair