BDBM50114440 2-(6-Chloro-benzothiazol-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL46876

SMILES: Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1nc2ccc(Cl)cc2s1

InChI Key: InChIKey=JTLHFYPDVWPLSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114440 (2-(6-Chloro-benzothiazol-2-yl)-5-methyl-2H-pyrazol...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1nc2ccc(Cl)cc2s1 Show InChI InChI=1S/C24H18ClN5O3S2/c1-14-12-20(30(29-14)24-28-19-11-8-16(25)13-21(19)34-24)23(31)27-17-9-6-15(7-10-17)18-4-2-3-5-22(18)35(26,32)33/h2-13H,1H3,(H,27,31)(H2,26,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against coagulation factor Xa				Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ
					More data for this Ligand-Target Pair