BDBM50114464 2-(3-Carbamimidoyl-phenoxy)-N-(2'-sulfamoyl-biphenyl-4-yl)-benzamide::CHEMBL43105

SMILES: NC(=N)c1cccc(Oc2ccccc2C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1

InChI Key: InChIKey=FUKVFZYOSCTXRM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114464 (2-(3-Carbamimidoyl-phenoxy)-N-(2'-sulfamoyl-biphen...) Show SMILES NC(=N)c1cccc(Oc2ccccc2C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1 Show InChI InChI=1S/C26H22N4O4S/c27-25(28)18-6-5-7-20(16-18)34-23-10-3-1-9-22(23)26(31)30-19-14-12-17(13-15-19)21-8-2-4-11-24(21)35(29,32)33/h1-16H,(H3,27,28)(H,30,31)(H2,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
					More data for this Ligand-Target Pair