BDBM50114467 2-(3-Carbamimidoyl-phenoxy)-4-methanesulfonylamino-N-(2'-sulfamoyl-biphenyl-4-yl)-benzamide::CHEMBL46410
SMILES: CS(=O)(=O)Nc1ccc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c(Oc2cccc(c2)C(N)=N)c1
InChI Key: InChIKey=GFTDNSMIRBLHTL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50114467 (2-(3-Carbamimidoyl-phenoxy)-4-methanesulfonylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa | Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T | |||||||||||
More data for this Ligand-Target Pair |