BDBM50114471 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-5-methanesulfonyl-phenyl]-amide::CHEMBL48725

SMILES: CS(=O)(=O)c1ccc(Oc2cccc(c2)C(N)=N)c(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1

InChI Key: InChIKey=NRTNLSLCHHNPNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114471 (2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...) Show SMILES CS(=O)(=O)c1ccc(Oc2cccc(c2)C(N)=N)c(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1 Show InChI InChI=1S/C27H24N4O6S2/c1-38(33,34)21-13-14-24(37-20-6-4-5-19(15-20)26(28)29)23(16-21)31-27(32)18-11-9-17(10-12-18)22-7-2-3-8-25(22)39(30,35)36/h2-16H,1H3,(H3,28,29)(H,31,32)(H2,30,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
					More data for this Ligand-Target Pair