BDBM50114488 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-ethyl]-furan-3-ylmethyl-amide::CHEMBL296005

SMILES: NC(=N)c1cccc(OCCN(Cc2ccoc2)C(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1

InChI Key: InChIKey=JHBIYDPEQQAZTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114488 (2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...) Show SMILES NC(=N)c1cccc(OCCN(Cc2ccoc2)C(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1 Show InChI InChI=1S/C27H26N4O5S/c28-26(29)22-4-3-5-23(16-22)36-15-13-31(17-19-12-14-35-18-19)27(32)21-10-8-20(9-11-21)24-6-1-2-7-25(24)37(30,33)34/h1-12,14,16,18H,13,15,17H2,(H3,28,29)(H2,30,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
					More data for this Ligand-Target Pair