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SMILES: NC(=N)c1cccc(OCC(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c2ccccc2)c1

InChI Key: InChIKey=YCGZOPNGEHECEH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114491   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50114491
PNG
(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Show SMILES NC(=N)c1cccc(OCC(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c2ccccc2)c1
Show InChI InChI=1S/C28H26N4O4S/c29-27(30)22-9-6-10-23(17-22)36-18-25(20-7-2-1-3-8-20)32-28(33)21-15-13-19(14-16-21)24-11-4-5-12-26(24)37(31,34)35/h1-17,25H,18H2,(H3,29,30)(H,32,33)(H2,31,34,35)
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PubMed
n/an/a 3.40n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the inhibitory activity against Coagulation factor Xa

Bioorg Med Chem Lett 12: 1657-61 (2002)


BindingDB Entry DOI: 10.7270/Q2R49Q2T
More data for this
Ligand-Target Pair