BindingDB PrimarySearch

BDBM50114872 CHEMBL3608450

SMILES: COc1cc2C(CN(C)C3Cc4cc5OCOc5cc4-c(c1OC)c23)c1ccccc1

InChI Key: InChIKey=XYYAWEJOUNEPTR-UHFFFAOYSA-N

Data: 7 KI 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50114872
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2C adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	627	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	719	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2A adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to PBR (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2B adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Agonist activity at 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair