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SMILES: FC(F)(F)c1cccc(c1)-n1c(csc1=N)-c1ccc(Cl)cc1

InChI Key: InChIKey=LPJSSRYUEBRCEV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus)	BDBM50115000 (4-(4-Chloro-phenyl)-3-(3-trifluoromethyl-phenyl)-3...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(csc1=N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H10ClF3N2S/c17-12-6-4-10(5-7-12)14-9-23-15(21)22(14)13-3-1-2-11(8-13)16(18,19)20/h1-9,21H	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranes				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50115000 (4-(4-Chloro-phenyl)-3-(3-trifluoromethyl-phenyl)-3...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(csc1=N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H10ClF3N2S/c17-12-6-4-10(5-7-12)14-9-23-15(21)22(14)13-3-1-2-11(8-13)16(18,19)20/h1-9,21H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissue				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50115000 (4-(4-Chloro-phenyl)-3-(3-trifluoromethyl-phenyl)-3...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(csc1=N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H10ClF3N2S/c17-12-6-4-10(5-7-12)14-9-23-15(21)22(14)13-3-1-2-11(8-13)16(18,19)20/h1-9,21H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranes				Bioorg Med Chem Lett 12: 1775-8 (2002) BindingDB Entry DOI: 10.7270/Q2Z038Q5
					More data for this Ligand-Target Pair