BDBM50115211 CHEMBL3609010

SMILES: OB(O)c1ccc(CNc2ncc(cn2)C(=O)Nc2ccc(F)cc2)cc1

InChI Key: InChIKey=QXTSCUBGBAJGQX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50115211 (CHEMBL3609010) Show SMILES OB(O)c1ccc(CNc2ncc(cn2)C(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C18H16BFN4O3/c20-15-5-7-16(8-6-15)24-17(25)13-10-22-18(23-11-13)21-9-12-1-3-14(4-2-12)19(26)27/h1-8,10-11,26-27H,9H2,(H,24,25)(H,21,22,23)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems Curated by ChEMBL					Assay Description Antagonist activity at CXCR1 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...				Bioorg Med Chem Lett 25: 3793-7 (2015) BindingDB Entry DOI: 10.7270/Q2V989VF
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50115211 (CHEMBL3609010) Show SMILES OB(O)c1ccc(CNc2ncc(cn2)C(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C18H16BFN4O3/c20-15-5-7-16(8-6-15)24-17(25)13-10-22-18(23-11-13)21-9-12-1-3-14(4-2-12)19(26)27/h1-8,10-11,26-27H,9H2,(H,24,25)(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...				Bioorg Med Chem Lett 25: 3793-7 (2015) BindingDB Entry DOI: 10.7270/Q2V989VF
					More data for this Ligand-Target Pair