null
SMILES: [#6]-c1ccnc2-[#6]-[#6](-[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c12)-c1ccsc1
InChI Key: InChIKey=KRXAXQAJANRMOO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/hydrogen exchanger 1 (Rattus norvegicus) | BDBM50115245 (CHEMBL554215 | N-[4-methyl-7-(3-thienyl)-5,6,7,8-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibition | J Med Chem 45: 3009-21 (2002) BindingDB Entry DOI: 10.7270/Q2V40VZN | |||||||||||
More data for this Ligand-Target Pair |