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BDBM50115305 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-pyridin-4-ylmethyl-phenyl)-amide::CHEMBL102330

SMILES: COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Cc4ccncc4)cc3)c2cc1OC

InChI Key: InChIKey=DNJDMYKOPAOKQC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115305   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50115305
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Cc4ccncc4)cc3)c2cc1OC
Show InChI InChI=1S/C27H28N6O3/c1-35-24-16-22-23(17-25(24)36-2)29-18-30-26(22)32-11-13-33(14-12-32)27(34)31-21-5-3-19(4-6-21)15-20-7-9-28-10-8-20/h3-10,16-18H,11-15H2,1-2H3,(H,31,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.04E+3n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor beta phosphorylation


J Med Chem 45: 3057-66 (2002)


BindingDB Entry DOI: 10.7270/Q2RX9BDP
More data for this
Ligand-Target Pair