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BDBM50115309 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-methanesulfinyl-phenyl)-amide::CHEMBL104427

SMILES: COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)S(C)=O)c2cc1OC

InChI Key: InChIKey=MUEDUMCTMMTQDB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115309   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta)


(Homo sapiens (human))
BDBM50115309
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)S(C)=O)c2cc1OC
Show InChI InChI=1S/C22H25N5O4S/c1-30-19-12-17-18(13-20(19)31-2)23-14-24-21(17)26-8-10-27(11-9-26)22(28)25-15-4-6-16(7-5-15)32(3)29/h4-7,12-14H,8-11H2,1-3H3,(H,25,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor beta phosphorylation


Citation and Details
More data for this
Ligand-Target Pair