BDBM50115316 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-ethyl-phenyl)-amide::CHEMBL320645

SMILES: CCc1ccc(NC(=O)N2CCN(CC2)c2ncnc3cc(OC)c(OC)cc23)cc1

InChI Key: InChIKey=RBMYTMOTFNHDMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50115316 (4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) Show SMILES CCc1ccc(NC(=O)N2CCN(CC2)c2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C23H27N5O3/c1-4-16-5-7-17(8-6-16)26-23(29)28-11-9-27(10-12-28)22-18-13-20(30-2)21(31-3)14-19(18)24-15-25-22/h5-8,13-15H,4,9-12H2,1-3H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor beta phosphorylation				J Med Chem 45: 3057-66 (2002) BindingDB Entry DOI: 10.7270/Q2RX9BDP
					More data for this Ligand-Target Pair