BDBM50115322 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid p-tolylamide::CHEMBL321286

SMILES: COc1cc2ncnc(N3CCN(CC3)C(=S)Nc3ccc(C)cc3)c2cc1OC

InChI Key: InChIKey=UHGNQJUWNBEJLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50115322 (4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=S)Nc3ccc(C)cc3)c2cc1OC Show InChI InChI=1S/C22H25N5O2S/c1-15-4-6-16(7-5-15)25-22(30)27-10-8-26(9-11-27)21-17-12-19(28-2)20(29-3)13-18(17)23-14-24-21/h4-7,12-14H,8-11H2,1-3H3,(H,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor beta phosphorylation				J Med Chem 45: 3057-66 (2002) BindingDB Entry DOI: 10.7270/Q2RX9BDP
					More data for this Ligand-Target Pair