BDBM50115349 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid [4-(4-nitro-phenoxy)-phenyl]-amide::CHEMBL319235

SMILES: COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)c2cc1OC

InChI Key: InChIKey=CUSJDZQXEFLELD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50115349 (4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)c2cc1OC Show InChI InChI=1S/C27H26N6O6/c1-37-24-15-22-23(16-25(24)38-2)28-17-29-26(22)31-11-13-32(14-12-31)27(34)30-18-3-7-20(8-4-18)39-21-9-5-19(6-10-21)33(35)36/h3-10,15-17H,11-14H2,1-2H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor beta phosphorylation				J Med Chem 45: 3057-66 (2002) BindingDB Entry DOI: 10.7270/Q2RX9BDP
					More data for this Ligand-Target Pair