BDBM50115353 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid (3-chloro-phenyl)-amide::CHEMBL103012
SMILES: COc1cc2ncnc(N3CCN(CC3)C(=S)Nc3cccc(Cl)c3)c2cc1OC
InChI Key: InChIKey=WRVCEMQBWLVDCT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50115353 (4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of Platelet-derived growth factor receptor beta phosphorylation | J Med Chem 45: 3057-66 (2002) BindingDB Entry DOI: 10.7270/Q2RX9BDP | |||||||||||
More data for this Ligand-Target Pair |