null
SMILES: CN(Cc1ccc(cn1)B(O)O)c1ncc(cn1)C(=O)Nc1ccc(F)cc1
InChI Key: InChIKey=ZVCRCHZYSCOVGC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50115371 (CHEMBL3609012) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 933 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntrix Biosystems Curated by ChEMBL | Assay Description Antagonist activity at CXCR2 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub... | Bioorg Med Chem Lett 25: 3793-7 (2015) BindingDB Entry DOI: 10.7270/Q2V989VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50115371 (CHEMBL3609012) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntrix Biosystems Curated by ChEMBL | Assay Description Antagonist activity at CXCR1 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub... | Bioorg Med Chem Lett 25: 3793-7 (2015) BindingDB Entry DOI: 10.7270/Q2V989VF | |||||||||||
More data for this Ligand-Target Pair |