BDBM50115510 2-{(4-Bromo-phenyl)-[1'-(2,6-dimethyl-benzoyl)-4'-methyl-[1,4']bipiperidinyl-4-yl]-methyleneaminooxy}-N-methyl-acetamide::CHEMBL106790
SMILES: CNC(=O)CO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)cccc1C)c1ccc(Br)cc1
InChI Key: InChIKey=AKFKVWRGZGPBHW-PJJLUWSFSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-C chemokine receptor type 5 (Mus musculus) | BDBM50115510 (2-{(4-Bromo-phenyl)-[1'-(2,6-dimethyl-benzoyl)-4'-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cells | J Med Chem 45: 3143-60 (2002) BindingDB Entry DOI: 10.7270/Q2HD7TZJ | |||||||||||
More data for this Ligand-Target Pair |