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BDBM50115532 4-[(Z)-(4-Bromophenyl)(ethoxyimino)methyl]-1'-[(2-hydroxy-4,6-dimethyl-3-pyridinyl)carbonyl]-4'-methyl-1,4'-bipiperidine::CHEMBL110730::{4-[(4-Bromo-phenyl)-ethoxyimino-methyl]-4'-methyl-[1,4']bipiperidinyl-1'-yl}-(2-hydroxy-4,6-dimethyl-pyridin-3-yl)-methanone

SMILES: CCO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)cc(C)[nH]c1=O)c1ccc(Br)cc1

InChI Key: InChIKey=NSNVDTQEDMRJDI-QCKNELIISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115532   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Mus musculus)		BDBM50115532
PNG
(4-[(Z)-(4-Bromophenyl)(ethoxyimino)methyl]-1'-[(2-...)
Show SMILES CCO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)cc(C)[nH]c1=O)c1ccc(Br)cc1
Show InChI InChI=1S/C28H37BrN4O3/c1-5-36-31-25(21-6-8-23(29)9-7-21)22-10-14-33(15-11-22)28(4)12-16-32(17-13-28)27(35)24-19(2)18-20(3)30-26(24)34/h6-9,18,22H,5,10-17H2,1-4H3,(H,30,34)/b31-25+
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 43n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cells

J Med Chem 45: 3143-60 (2002)


BindingDB Entry DOI: 10.7270/Q2HD7TZJ
More data for this
Ligand-Target Pair