BDBM50115715 5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-carbonitrile::CHEMBL56118

SMILES: N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1

InChI Key: InChIKey=IKBANCXZZJPIEB-UHFFFAOYSA-N

Data: 7 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50115715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cells				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]8-OH-DPAT radioligand from porcine 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (PIG)	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-Ketanserin radioligand from porcine 5-hydroxytryptamine 2A receptor				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D3 in CHO cells				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]SCH-23390 radioligand from cloned human Dopamine receptor D2 in CHO cells				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]SCH-23,390 radioligand from bovine Dopamine receptor D1				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cells				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50115715 (5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...) Show SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C16H18N4/c17-11-14-10-15(18-12-14)13-19-6-8-20(9-7-19)16-4-2-1-3-5-16/h1-5,10,12,18H,6-9,13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cells				Bioorg Med Chem Lett 12: 1937-40 (2002) BindingDB Entry DOI: 10.7270/Q2T72J0V
					More data for this Ligand-Target Pair