BDBM50115731 4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic acid methyl ester::CHEMBL301254

SMILES: COC(=O)c1ccc(cc1)C1=CC(=O)C(=O)c2ccccc12

InChI Key: InChIKey=BRCFETUVTSSJSP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50115731 (4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...) Show SMILES COC(=O)c1ccc(cc1)C1=CC(=O)C(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C18H12O4/c1-22-18(21)12-8-6-11(7-9-12)15-10-16(19)17(20)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Leukocyte common antigen (Homo sapiens (Human))	BDBM50115731 (4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...) Show SMILES COC(=O)c1ccc(cc1)C1=CC(=O)C(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C18H12O4/c1-22-18(21)12-8-6-11(7-9-12)15-10-16(19)17(20)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human CD45 using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50115731 (4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...) Show SMILES COC(=O)c1ccc(cc1)C1=CC(=O)C(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C18H12O4/c1-22-18(21)12-8-6-11(7-9-12)15-10-16(19)17(20)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human Cdc25B using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50115731 (4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...) Show SMILES COC(=O)c1ccc(cc1)C1=CC(=O)C(=O)c2ccccc12 |t:11| Show InChI InChI=1S/C18H12O4/c1-22-18(21)12-8-6-11(7-9-12)15-10-16(19)17(20)14-5-3-2-4-13(14)15/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human LAR using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair