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SMILES: CN(C)CCn1c(=O)\c(=C\c2ccc3OCOc3c2)s\c1=C1/C(=O)Nc2ccccc12

InChI Key: InChIKey=DYQUPEWWEWCFBW-PCZWAXSUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50115984   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50115984
PNG
(CHEMBL3612175)
Show SMILES CN(C)CCn1c(=O)\c(=C\c2ccc3OCOc3c2)s\c1=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C23H21N3O4S/c1-25(2)9-10-26-22(28)19(12-14-7-8-17-18(11-14)30-13-29-17)31-23(26)20-15-5-3-4-6-16(15)24-21(20)27/h3-8,11-12H,9-10,13H2,1-2H3,(H,24,27)/b19-12-,23-20-
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>2.23E+3n/an/an/an/an/an/an/an/a



The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry

Eur J Med Chem 101: 126-32 (2015)


BindingDB Entry DOI: 10.7270/Q2PN97FH
More data for this
Ligand-Target Pair