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BDBM50116024 4-[4-(4-Fluoro-phenyl)-thiazol-5-yl]-pyridine::CHEMBL294052

SMILES: Fc1ccc(cc1)-c1ncsc1-c1ccncc1

InChI Key: InChIKey=IYDSUKQRNVOVBV-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116024   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase p38


(Mus musculus (mouse))
BDBM50116024
PNG
(4-[4-(4-Fluoro-phenyl)-thiazol-5-yl]-pyridine | CH...)
Show SMILES Fc1ccc(cc1)-c1ncsc1-c1ccncc1
Show InChI InChI=1S/C14H9FN2S/c15-12-3-1-10(2-4-12)13-14(18-9-17-13)11-5-7-16-8-6-11/h1-9H
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 800n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATP


Bioorg Med Chem Lett 12: 2109-12 (2002)


BindingDB Entry DOI: 10.7270/Q2610ZNX
More data for this
Ligand-Target Pair