null

SMILES: Nc1nc(N)c(F)c(-c2nc(-c3ccco3)c([nH]2)-c2ccncc2)c1F

InChI Key: InChIKey=YQJXZKKQJNGAQW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Mus musculus (mouse))	BDBM50116027 (3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...) Show SMILES Nc1nc(N)c(F)c(-c2nc(-c3ccco3)c([nH]2)-c2ccncc2)c1F Show InChI InChI=1S/C17H12F2N6O/c18-11-10(12(19)16(21)25-15(11)20)17-23-13(8-3-5-22-6-4-8)14(24-17)9-2-1-7-26-9/h1-7H,(H,23,24)(H4,20,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATP				Bioorg Med Chem Lett 12: 2109-12 (2002) BindingDB Entry DOI: 10.7270/Q2610ZNX
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50116027 (3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...) Show SMILES Nc1nc(N)c(F)c(-c2nc(-c3ccco3)c([nH]2)-c2ccncc2)c1F Show InChI InChI=1S/C17H12F2N6O/c18-11-10(12(19)16(21)25-15(11)20)17-23-13(8-3-5-22-6-4-8)14(24-17)9-2-1-7-26-9/h1-7H,(H,23,24)(H4,20,21,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIA				Bioorg Med Chem Lett 12: 2109-12 (2002) BindingDB Entry DOI: 10.7270/Q2610ZNX
					More data for this Ligand-Target Pair