BDBM50116237 6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-methyl]-8-(2-fluoro-benzyl)-2-(4-methoxy-phenyl)-7-methyl-8H-imidazo[1,2-a]pyrimidin-5-one::CHEMBL306431

SMILES: COc1ccc(cc1)-c1nc2n(Cc3ccccc3F)c(C)c(-c3ccc4OCOc4c3)c(=O)n2c1CN(C)Cc1ccccc1

InChI Key: InChIKey=UEQIOCUCOGQZDQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50116237 (6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-m...) Show SMILES COc1ccc(cc1)-c1nc2n(Cc3ccccc3F)c(C)c(-c3ccc4OCOc4c3)c(=O)n2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H33FN4O4/c1-24-34(27-15-18-32-33(19-27)46-23-45-32)36(43)42-31(22-40(2)20-25-9-5-4-6-10-25)35(26-13-16-29(44-3)17-14-26)39-37(42)41(24)21-28-11-7-8-12-30(28)38/h4-19H,20-23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of GnRH receptor				Bioorg Med Chem 16: 422-7 (2008) Article DOI: 10.1016/j.bmc.2007.09.026 BindingDB Entry DOI: 10.7270/Q2Z60PXR
					More data for this Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50116237 (6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-m...) Show SMILES COc1ccc(cc1)-c1nc2n(Cc3ccccc3F)c(C)c(-c3ccc4OCOc4c3)c(=O)n2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H33FN4O4/c1-24-34(27-15-18-32-33(19-27)46-23-45-32)36(43)42-31(22-40(2)20-25-9-5-4-6-10-25)35(26-13-16-29(44-3)17-14-26)39-37(42)41(24)21-28-11-7-8-12-30(28)38/h4-19H,20-23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding evaluated in cloned human Gonadotropin-releasing hormone receptor by displacement of [125 I-Tyr, DLeu, NMeLeu, Pro-NEt]GnRH agonist				Bioorg Med Chem Lett 12: 2185-7 (2002) BindingDB Entry DOI: 10.7270/Q2513XJ0
					More data for this Ligand-Target Pair