BDBM50116600 CHEMBL325475::N-(9-Ethyl-9H-carbazol-3-yl)-3-pyridin-4-yl-propionamide

SMILES: CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12

InChI Key: InChIKey=STJCFOPXJIECBK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50116600 (CHEMBL325475 | N-(9-Ethyl-9H-carbazol-3-yl)-3-pyri...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12 Show InChI InChI=1S/C22H21N3O/c1-2-25-20-6-4-3-5-18(20)19-15-17(8-9-21(19)25)24-22(26)10-7-16-11-13-23-14-12-16/h3-6,8-9,11-15H,2,7,10H2,1H3,(H,24,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)				J Med Chem 45: 3509-23 (2002) BindingDB Entry DOI: 10.7270/Q27S7N3K
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50116600 (CHEMBL325475 | N-(9-Ethyl-9H-carbazol-3-yl)-3-pyri...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12 Show InChI InChI=1S/C22H21N3O/c1-2-25-20-6-4-3-5-18(20)19-15-17(8-9-21(19)25)24-22(26)10-7-16-11-13-23-14-12-16/h3-6,8-9,11-15H,2,7,10H2,1H3,(H,24,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Compound was evaluated in vitro for human Neuropeptide Y receptor Y5 functional antagonism (reporter gene assay)				J Med Chem 45: 3509-23 (2002) BindingDB Entry DOI: 10.7270/Q27S7N3K
					More data for this Ligand-Target Pair
NPY5R (Rat 6B)	BDBM50116600 (CHEMBL325475 | N-(9-Ethyl-9H-carbazol-3-yl)-3-pyri...) Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12 Show InChI InChI=1S/C22H21N3O/c1-2-25-20-6-4-3-5-18(20)19-15-17(8-9-21(19)25)24-22(26)10-7-16-11-13-23-14-12-16/h3-6,8-9,11-15H,2,7,10H2,1H3,(H,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity against rat Neuropeptide Y receptor Y5				J Med Chem 45: 3509-23 (2002) BindingDB Entry DOI: 10.7270/Q27S7N3K
					More data for this Ligand-Target Pair