BDBM50117657 CHEMBL3613702

SMILES: Fc1cc(Nc2ncnc3ccc(NC(=O)C=C)cc23)cc(Cl)c1Cl

InChI Key: InChIKey=GGBRHDVTKTXRBX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50117657 (CHEMBL3613702) Show SMILES Fc1cc(Nc2ncnc3ccc(NC(=O)C=C)cc23)cc(Cl)c1Cl Show InChI InChI=1S/C17H11Cl2FN4O/c1-2-15(25)23-9-3-4-14-11(5-9)17(22-8-21-14)24-10-6-12(18)16(19)13(20)7-10/h2-8H,1H2,(H,23,25)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.0370	n/a	n/a	n/a	n/a	n/a	n/a
Jazan University Curated by ChEMBL					Assay Description Inhibition of epidermal growth factor receptor kinase (unknown origin) using [33P]-ATP after 20 to 30 mins by radiometric assay				Eur J Med Chem 102: 115-31 (2015) BindingDB Entry DOI: 10.7270/Q2JQ12TS
					More data for this Ligand-Target Pair