BDBM50117961 (6,7-Diethoxy-quinazolin-4-yl)-[3-(1H-[1,2,4]triazol-3-yl)-phenyl]-amine::CHEMBL127367

SMILES: CCOc1cc2ncnc(Nc3cccc(c3)-c3nnc[nH]3)c2cc1OCC

InChI Key: InChIKey=WGTILZRWWWHQLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50117961 ((6,7-Diethoxy-quinazolin-4-yl)-[3-(1H-[1,2,4]triaz...) Show SMILES CCOc1cc2ncnc(Nc3cccc(c3)-c3nnc[nH]3)c2cc1OCC Show InChI InChI=1S/C20H20N6O2/c1-3-27-17-9-15-16(10-18(17)28-4-2)21-11-22-20(15)25-14-7-5-6-13(8-14)19-23-12-24-26-19/h5-12H,3-4H2,1-2H3,(H,21,22,25)(H,23,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Inhibition of (EGFR) epidermal growth factor receptor tyrosine kinase				J Med Chem 45: 3865-77 (2002) BindingDB Entry DOI: 10.7270/Q2PN94Z0
					More data for this Ligand-Target Pair