BDBM50118044 1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoromethylsulfanyl-benzyl)-amino]-propan-2-ol::1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(trifluoromethylthio)benzyl)amino)propan-2-ol::CHEMBL129412

SMILES: OC(CN(Cc1cccc(SC(F)(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F

InChI Key: InChIKey=IPVGULVLTUJMGW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50118044 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES OC(CN(Cc1cccc(SC(F)(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F Show InChI InChI=1S/C23H19F6NO2S/c24-22(25,26)21(31)15-30(14-16-6-4-11-20(12-16)33-23(27,28)29)17-7-5-10-19(13-17)32-18-8-2-1-3-9-18/h1-13,21,31H,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50118044 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES OC(CN(Cc1cccc(SC(F)(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F Show InChI InChI=1S/C23H19F6NO2S/c24-22(25,26)21(31)15-30(14-16-6-4-11-20(12-16)33-23(27,28)29)17-7-5-10-19(13-17)32-18-8-2-1-3-9-18/h1-13,21,31H,14-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50118044 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES OC(CN(Cc1cccc(SC(F)(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F Show InChI InChI=1S/C23H19F6NO2S/c24-22(25,26)21(31)15-30(14-16-6-4-11-20(12-16)33-23(27,28)29)17-7-5-10-19(13-17)32-18-8-2-1-3-9-18/h1-13,21,31H,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Inhibition of cholesteryl ester transfer protein in presence of human serum				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
					More data for this Ligand-Target Pair