Found 4 hits for monomerid = 50118334 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50118334
(CHEMBL3612507)Show SMILES CN(\N=C\c1cnn2ccc(nc12)C#N)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C16H13N7O4S/c1-11-3-4-14(23(24)25)7-15(11)28(26,27)21(2)18-9-12-10-19-22-6-5-13(8-17)20-16(12)22/h3-7,9-10H,1-2H3/b18-9+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Melbourne
Curated by ChEMBL
| Assay Description
Inhibition of CDK7 (unknown origin) by radiometric assay |
Bioorg Med Chem 23: 6280-96 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DM6 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50118334
(CHEMBL3612507)Show SMILES CN(\N=C\c1cnn2ccc(nc12)C#N)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C16H13N7O4S/c1-11-3-4-14(23(24)25)7-15(11)28(26,27)21(2)18-9-12-10-19-22-6-5-13(8-17)20-16(12)22/h3-7,9-10H,1-2H3/b18-9+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.212 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Melbourne
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 (unknown origin) using biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 as substrate after 90 mins b... |
Bioorg Med Chem 23: 6280-96 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DM6 |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50118334
(CHEMBL3612507)Show SMILES CN(\N=C\c1cnn2ccc(nc12)C#N)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C16H13N7O4S/c1-11-3-4-14(23(24)25)7-15(11)28(26,27)21(2)18-9-12-10-19-22-6-5-13(8-17)20-16(12)22/h3-7,9-10H,1-2H3/b18-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Melbourne
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human CDK9/cyclin-T1 using H-YSPTSPSYSPTSPSYSPTSPS-KKKK-OH as substrate after 90 mins by luminescence assay |
Bioorg Med Chem 23: 6280-96 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DM6 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50118334
(CHEMBL3612507)Show SMILES CN(\N=C\c1cnn2ccc(nc12)C#N)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C16H13N7O4S/c1-11-3-4-14(23(24)25)7-15(11)28(26,27)21(2)18-9-12-10-19-22-6-5-13(8-17)20-16(12)22/h3-7,9-10H,1-2H3/b18-9+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 198 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Melbourne
Curated by ChEMBL
| Assay Description
Inhibition of PI3Kalpha (unknown origin) by radiometric assay |
Bioorg Med Chem 23: 6280-96 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DM6 |
More data for this
Ligand-Target Pair | |
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