BDBM50118478 CHEMBL3613749
SMILES: Cc1ncc(Cl)cc1NCc1ccc(s1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1
InChI Key: InChIKey=IVDUVEGCMXCMSO-FQEVSTJZSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein phosphatase 1D (Homo sapiens (Human)) | BDBM50118478 (CHEMBL3613749) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N... | Bioorg Med Chem 23: 6246-9 (2015) BindingDB Entry DOI: 10.7270/Q26975C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein phosphatase 1D (Homo sapiens (Human)) | BDBM50118478 (CHEMBL3613749) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein phosphatase 1D (Homo sapiens (Human)) | BDBM50118478 (CHEMBL3613749) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus-infected insect SF9 cells assessed as fluorescein diphosphate hydrolysis after ... | J Med Chem 59: 6629-44 (2016) Article DOI: 10.1021/acs.jmedchem.5b01874 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein phosphatase 1D (Homo sapiens (Human)) | BDBM50118478 (CHEMBL3613749) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus-infected insect SF9 cells assessed as fluorescein diphosphate hydrolysis after ... | J Med Chem 59: 6629-44 (2016) Article DOI: 10.1021/acs.jmedchem.5b01874 | |||||||||||
More data for this Ligand-Target Pair |