BDBM50118701 6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoquinoline-3-carboxylic acid; hydrochloride::CHEMBL542242

SMILES: OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1

InChI Key: InChIKey=CQEYRNLQNUBIGU-YFKTTZPYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50118701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA2 (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
GRIA1 (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.34E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.36E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]KA to recombinant human KA receptor Ionotropic glutamate receptor ionotropic kainate 2 expressed in EK 293 cell me...				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.47E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 3				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.62E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50118701 (6-(4-Carboxy-imidazol-1-ylmethyl)-decahydro-isoqui...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cn3cnc(c3)C(O)=O)CC[C@H]2CN1 Show InChI InChI=1S/C15H21N3O4/c19-14(20)12-4-11-3-9(1-2-10(11)5-16-12)6-18-7-13(15(21)22)17-8-18/h7-12,16H,1-6H2,(H,19,20)(H,21,22)/t9-,10-,11+,12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human AMPA receptor Ionotropic glutamate receptor ionotropic kainate 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair