Found 12 hits for monomerid = 50118744 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor-type tyrosine-protein phosphatase beta
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPRB |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate University of Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Binding affinity to PTP1B |
Bioorg Med Chem Lett 15: 5521-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.078 BindingDB Entry DOI: 10.7270/Q2TF0139 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB PubMed
| 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5. |
J Med Chem 45: 4443-59 (2002)
BindingDB Entry DOI: 10.7270/Q2QJ7GM5 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPN2 |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tsinghua University
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant PTP1B |
Bioorg Med Chem Lett 20: 3329-37 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.033 BindingDB Entry DOI: 10.7270/Q27D2WCC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Receptor-type tyrosine-protein phosphatase epsilon
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPRE |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase C
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPRC |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase alpha
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPRA |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase alpha
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5. |
J Med Chem 45: 4443-59 (2002)
BindingDB Entry DOI: 10.7270/Q2QJ7GM5 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPN6 |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase F
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Miami
Curated by ChEMBL
| Assay Description Inhibition of PTPRF |
J Med Chem 52: 6649-59 (2009)
Article DOI: 10.1021/jm9008899 BindingDB Entry DOI: 10.7270/Q29023T5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase F
(Homo sapiens (Human)) | BDBM50118744
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran...)Show InChI InChI=1S/C10H9NO6S/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5. |
J Med Chem 45: 4443-59 (2002)
BindingDB Entry DOI: 10.7270/Q2QJ7GM5 |
More data for this Ligand-Target Pair | |