BDBM50118914 CHEMBL343739::Phenyl-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-methanone::Phenyl-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-methanone

SMILES: O=C([C@@H]1CCCN1C(=O)c1ccccc1)N1CCCC1

InChI Key: InChIKey=HEWFDUPRLUFDCZ-AWEZNQCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Sus scrofa)	BDBM50118914 (CHEMBL343739 | Phenyl-[(S)-2-(pyrrolidine-1-carbon...) Show SMILES O=C([C@@H]1CCCN1C(=O)c1ccccc1)N1CCCC1 Show InChI InChI=1S/C16H20N2O2/c19-15(13-7-2-1-3-8-13)18-12-6-9-14(18)16(20)17-10-4-5-11-17/h1-3,7-8,14H,4-6,9-12H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	7.0	n/a
University of Kuopio Curated by ChEMBL					Assay Description In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...				J Med Chem 48: 4772-82 (2005) Article DOI: 10.1021/jm0500020 BindingDB Entry DOI: 10.7270/Q22B8ZT2
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Sus scrofa)	BDBM50118914 (CHEMBL343739 | Phenyl-[(S)-2-(pyrrolidine-1-carbon...) Show SMILES O=C([C@@H]1CCCN1C(=O)c1ccccc1)N1CCCC1 Show InChI InChI=1S/C16H20N2O2/c19-15(13-7-2-1-3-8-13)18-12-6-9-14(18)16(20)17-10-4-5-11-17/h1-3,7-8,14H,4-6,9-12H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against prolyl oligopeptidase (POP) from pig brain ;value ranges from (38-110)				J Med Chem 45: 4581-4 (2002) BindingDB Entry DOI: 10.7270/Q22R3R02
					More data for this Ligand-Target Pair