BDBM50118946 (S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione::CHEMBL97483
SMILES: C[C@H](N)C(=S)N1CCCC1
InChI Key: InChIKey=JUPUJRCJICHRIW-LURJTMIESA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50118946 ((S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione | C...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibition of Dipeptidyl Peptidase II (Quiescent cell proline peptidase) | Bioorg Med Chem Lett 12: 2825-8 (2002) BindingDB Entry DOI: 10.7270/Q279457M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50118946 ((S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione | C...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II) | J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50118946 ((S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 4.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory activity of compound against Dipeptidylpeptidase IV (DPP IV) | J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50118946 ((S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 4.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibition of Dipeptidyl Peptidase IV | Bioorg Med Chem Lett 12: 2825-8 (2002) BindingDB Entry DOI: 10.7270/Q279457M | |||||||||||
More data for this Ligand-Target Pair |