null

SMILES: COc1ccc(cc1)-n1nc(cc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC1)C(=O)NCC1CCCO1

InChI Key: InChIKey=DFJPPDOTRUJQBY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50119484 (1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC1)C(=O)NCC1CCCO1 Show InChI InChI=1S/C28H31N5O5/c1-37-22-12-10-21(11-13-22)33-25(17-24(31-33)26(34)29-18-23-5-4-16-38-23)27(35)30-20-8-6-19(7-9-20)28(36)32-14-2-3-15-32/h6-13,17,23H,2-5,14-16,18H2,1H3,(H,29,34)(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pylori				J Med Chem 45: 4669-78 (2002) BindingDB Entry DOI: 10.7270/Q2C24VSW
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50119484 (1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...) Show SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC1)C(=O)NCC1CCCO1 Show InChI InChI=1S/C28H31N5O5/c1-37-22-12-10-21(11-13-22)33-25(17-24(31-33)26(34)29-18-23-5-4-16-38-23)27(35)30-20-8-6-19(7-9-20)28(36)32-14-2-3-15-32/h6-13,17,23H,2-5,14-16,18H2,1H3,(H,29,34)(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human dihydroorotate dehydrogenase (DHODase)				J Med Chem 45: 4669-78 (2002) BindingDB Entry DOI: 10.7270/Q2C24VSW
					More data for this Ligand-Target Pair