BDBM50119631 5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol::CHEMBL144958::NOHEP

SMILES: O=c1ccc(c[nH]1)[C@H]1CC2CCC1N2

InChI Key: InChIKey=DFBQWJREWVWEKO-HWOCKDDLSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholinergic, Nicotinic Alpha2Beta2 (Xenopus)	BDBM50119631 (5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...) Show SMILES O=c1ccc(c[nH]1)[C@H]1CC2CCC1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H14N2O/c14-11-4-1-7(6-12-11)9-5-8-2-3-10(9)13-8/h1,4,6,8-10,13H,2-3,5H2,(H,12,14)/t8?,9-,10?/m1/s1	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Miami Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 1246-52 (2002) Article DOI: 10.1124/jpet.102.035899 BindingDB Entry DOI: 10.7270/Q2HQ3XG3
					More data for this Ligand-Target Pair
Cholinergic, Nicotinic Alpha3Beta2 (Xenopus)	BDBM50119631 (5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...) Show SMILES O=c1ccc(c[nH]1)[C@H]1CC2CCC1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H14N2O/c14-11-4-1-7(6-12-11)9-5-8-2-3-10(9)13-8/h1,4,6,8-10,13H,2-3,5H2,(H,12,14)/t8?,9-,10?/m1/s1	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Miami Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 1246-52 (2002) Article DOI: 10.1124/jpet.102.035899 BindingDB Entry DOI: 10.7270/Q2HQ3XG3
					More data for this Ligand-Target Pair
Cholinergic, Nicotinic Alpha4Beta2 (Xenopus)	BDBM50119631 (5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...) Show SMILES O=c1ccc(c[nH]1)[C@H]1CC2CCC1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H14N2O/c14-11-4-1-7(6-12-11)9-5-8-2-3-10(9)13-8/h1,4,6,8-10,13H,2-3,5H2,(H,12,14)/t8?,9-,10?/m1/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Miami Curated by PDSP Ki Database									J Pharmacol Exp Ther 302: 1246-52 (2002) Article DOI: 10.1124/jpet.102.035899 BindingDB Entry DOI: 10.7270/Q2HQ3XG3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50119631 (5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...) Show SMILES O=c1ccc(c[nH]1)[C@H]1CC2CCC1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H14N2O/c14-11-4-1-7(6-12-11)9-5-8-2-3-10(9)13-8/h1,4,6,8-10,13H,2-3,5H2,(H,12,14)/t8?,9-,10?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	675	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [125I]- iodo-MLA binding at the Nicotinic acetylcholine receptor alpha-7 (nAChR) in male rat cerebral cortex				J Med Chem 45: 4755-61 (2002) BindingDB Entry DOI: 10.7270/Q2S18362
					More data for this Ligand-Target Pair