BindingDB logo
myBDB logout

BDBM50119729 CHEMBL102853::Cyclopropyl-(4-{3-[(1S,4S)-5-(furan-2-carbonyl)-2,5-diaza-bicyclo[2.2.1]hept-2-yl]-propoxy}-phenyl)-methanone

SMILES: O=C(C1CC1)c1ccc(OCCCN2C[C@@H]3C[C@H]2CN3C(=O)c2ccco2)cc1

InChI Key: InChIKey=CEIWOAFDGZPVTP-OALUTQOASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119729   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50119729
PNG
(CHEMBL102853 | Cyclopropyl-(4-{3-[(1S,4S)-5-(furan...)
Show SMILES O=C(C1CC1)c1ccc(OCCCN2C[C@@H]3C[C@H]2CN3C(=O)c2ccco2)cc1
Show InChI InChI=1S/C23H26N2O4/c26-22(16-4-5-16)17-6-8-20(9-7-17)28-12-2-10-24-14-19-13-18(24)15-25(19)23(27)21-3-1-11-29-21/h1,3,6-9,11,16,18-19H,2,4-5,10,12-15H2/t18-,19-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 208n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against rat histamine H3 receptor

Bioorg Med Chem Lett 12: 3055-8 (2002)


BindingDB Entry DOI: 10.7270/Q2B56J3P
More data for this
Ligand-Target Pair