BDBM50119877 CHEMBL3616517

SMILES: On1c(=O)n(CCCc2ccccc2)c2ncn(CCc3ccccc3)c2c1=O

InChI Key: InChIKey=ZWLOFVLXNOZKNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CCR4-NOT transcription complex subunit 7 (Homo sapiens (Human))	BDBM50119877 (CHEMBL3616517) Show SMILES On1c(=O)n(CCCc2ccccc2)c2ncn(CCc3ccccc3)c2c1=O Show InChI InChI=1S/C22H22N4O3/c27-21-19-20(23-16-24(19)15-13-18-10-5-2-6-11-18)25(22(28)26(21)29)14-7-12-17-8-3-1-4-9-17/h1-6,8-11,16,29H,7,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of human poly(A)-selective ribonuclease Caf1 by fluorescence-based assay				Bioorg Med Chem Lett 25: 4219-24 (2015) BindingDB Entry DOI: 10.7270/Q2BV7JFF
					More data for this Ligand-Target Pair